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Image Search Results
Journal: BMJ Open
Article Title: Lack of association between the brain penetrance of calcium channel blockers and the incidence of neuropsychiatric outcomes: a retrospective, multidatabase cohort study
doi: 10.1136/bmjopen-2025-100282
Figure Lengend Snippet: Primary analysis using an ITT design for each of the four outcomes. Results are shown within each database, separately for each outcome: ( A ) schizophrenia as the outcome; ( B ) schizoaffective disorder as the outcome; ( C ) major depressive disorder as the outcome; ( D ) bipolar disorder as the outcome. Events occurring in fewer than five patients are reported as ‘<5’ in accordance with data use agreements. Calibrated risk ratios are comparing the risk of the outcome among patients initiating brain-penetrant CCBs with the risk among patients initiating non-brain-penetrant CCBs. IRs are per 1000 person-years. Note that results are presented for all databases regardless of diagnostic status, though meta-analyses only include results that passed relevant diagnostics. BP-CCBs, brain-penetrant calcium channel blockers; EHR, electronic health record; IR, incidence rate; ITT, intent-to-treat; NP-CCBs, non-brain-penetrant calcium channel blockers; SDM, standardised difference of mean.
Article Snippet: Databases included the (1) Merative MarketScan Commercial Database (CCAE), (2) Merative MarketScan Multi-State Medicaid Database (MDCD), (3) Merative MarketScan Medicare Supplemental Database (MDCR), (4) Optum Clinformatics Data Mart (Optum Clinformatics), (5) The IQVIA Adjudicated Health Plan Claims Data (PharMetrics Plus), (6) IQVIA Disease Analyzer Germany (IQVIA Germany), (7) Japanese Claims Data (JMDC), (8) IQVIA longitudinal patient data in Australia (IQVIA Australia) and (9)
Techniques: Diagnostic Assay
Journal: BMJ Open
Article Title: Lack of association between the brain penetrance of calcium channel blockers and the incidence of neuropsychiatric outcomes: a retrospective, multidatabase cohort study
doi: 10.1136/bmjopen-2025-100282
Figure Lengend Snippet: Secondary analysis, requiring at least 180 days of continuous exposure, at-risk period starting at day 180. Results are shown within each database, separately for each outcome: ( A ) schizophrenia as the outcome; ( B ) schizoaffective disorder as the outcome; ( C ) major depressive disorder as the outcome; ( D ) bipolar disorder as the outcome. Events occurring in fewer than five patients are reported as ‘<5’ in accordance with data use agreements. Note that results are presented for all databases regardless of diagnostic status, though meta-analyses only include results that passed relevant diagnostics. BP CCBs, brain-penetrant calcium channel blockers; EHR, electronic health record; IR, incidence rate (per 1000 person-years); NP-CCBs, non-brain penetrant calcium channel blockers; SDM, standardised difference of mean.
Article Snippet: Databases included the (1) Merative MarketScan Commercial Database (CCAE), (2) Merative MarketScan Multi-State Medicaid Database (MDCD), (3) Merative MarketScan Medicare Supplemental Database (MDCR), (4) Optum Clinformatics Data Mart (Optum Clinformatics), (5) The IQVIA Adjudicated Health Plan Claims Data (PharMetrics Plus), (6) IQVIA Disease Analyzer Germany (IQVIA Germany), (7) Japanese Claims Data (JMDC), (8) IQVIA longitudinal patient data in Australia (IQVIA Australia) and (9)
Techniques: Diagnostic Assay
Journal: JMIR Diabetes
Article Title: Identifying Patients With Hypoglycemia Using Natural Language Processing: Systematic Literature Review
doi: 10.2196/34681
Figure Lengend Snippet: Summary of studies on natural language processing (NLP) and hypoglycemia.
Article Snippet: Nunes et al, 2016 [ ], United States , Optum
Techniques: Diagnostic Assay, Modification, Generated